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safe2184185 artist:latecustomer334 twilight sparkle359257 alicorn316425 pony1612941 g42040985 angry36804 boop9367 crossover73336 donatello147 female1813697 floppy ears73425 funny5514 glare9071 mare748216 monochrome175518 nose wrinkle3933 open mouth239583 raised eyebrow9970 raised hoof70552 spread wings95686 surprised12860 teenage mutant ninja turtles824 twilight sparkle (alicorn)149975 twilight sparkle is not amused2012 unamused24139 wallpaper20874 yelling4327

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evil_eric

he ate Good Eric
Comic book logic distinguishes between mutants (born with genetic aberrations) and mutates (have genetic aberrations imposed on them later in life). The X-Men are mutants, since they were born with it, while Spider-Man is a mutate, since his DNA was rearranged later on. By that logic, Twilight would be a mutate…and technically, so would the Turtles.
Scrounge
My Little Pony - 1992 Edition
Wallet After Summer Sale -
Not a Llama - Happy April Fools Day!
Since the Beginning  -

nobody's favorite
Of course she’s not a mutant!
 
If you deliberately cause it, it’s not mutation, it’s genetic engineering!
Vitruvius
Non-Fungible Trixie -
The End wasn't The End - Found a new home after the great exodus of 2012

@amess  
It turns out that the overwhelming majority of mutations are completely unnoticeable. It’s estimated that each person carries about 100 minor mutations, not inherited from either the mother or the father.
amess

@BigMax  
Yeah, real mutations have about the same chance of turning out good as does accessing your computers bios, sitting on the keyboard and activating the resulting code.