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Champions of Equestria

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safe2174425 artist:latecustomer334 twilight sparkle357756 alicorn314140 pony1602547 g42028941 angry36663 boop9320 crossover73105 donatello147 female1802762 floppy ears72982 funny5490 glare9054 mare741075 monochrome175013 nose wrinkle3908 open mouth237549 raised eyebrow9904 raised hoof69942 spread wings94524 surprised12793 teenage mutant ninja turtles823 twilight sparkle (alicorn)149127 twilight sparkle is not amused2007 unamused24026 wallpaper20829 yelling4308

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evil_eric

he ate Good Eric
Comic book logic distinguishes between mutants (born with genetic aberrations) and mutates (have genetic aberrations imposed on them later in life). The X-Men are mutants, since they were born with it, while Spider-Man is a mutate, since his DNA was rearranged later on. By that logic, Twilight would be a mutate…and technically, so would the Turtles.
Scrounge
My Little Pony - 1992 Edition
Wallet After Summer Sale -
Not a Llama - Happy April Fools Day!
Since the Beginning  -

nobody's favorite
Of course she’s not a mutant!
 
If you deliberately cause it, it’s not mutation, it’s genetic engineering!
Vitruvius
Non-Fungible Trixie -
The End wasn't The End - Found a new home after the great exodus of 2012

@amess  
It turns out that the overwhelming majority of mutations are completely unnoticeable. It’s estimated that each person carries about 100 minor mutations, not inherited from either the mother or the father.
amess

@BigMax  
Yeah, real mutations have about the same chance of turning out good as does accessing your computers bios, sitting on the keyboard and activating the resulting code.