Oh wow, those immortal alicorns who rule the country have it so hard, not having any parents.
 
Should have just been Spike.

@Evowizard25  
Twilight treats him pretty lovingly, nine times out of ten, and when she’s harsh with him, it’s deserved. Or playful. And Rarity, even if she doesn’t return his feelings, still cares about him deeply. She had the strongest reaction to him being threatened by the teenage dragons, for instance.
 
So he’s probably closest to Twilight, followed by Applejack and Rarity; take your pick which one gets #2 and #3.

Rarity? Motherly? HA!
 
Applejack is the only pony who is constantly nice to him and always makes sure he’s alright. {Remember in ‘Over A Barrel’. Applejack was the only one to run over to Spike when he returned. And in ‘Castle Mania’, when he got launched by a trap, she was the only one watching in terror as he got flung around.}
 
I’m just saying. Even though Twilight is nice to him, she’s more of a big sister, so she tends to neglect him.
 
Of course, if we go by what Faust intended, Celestia raised Spike. So Celestia is his mother…by adoption. {I enjoy that idea and I hate how the show doesn’t capitalizes it.}
 
So as I was saying. Spike’s pretty much an Apple in Applejack’s mind.

MLP is clearly from comic book writers…

Poor Spike. When you put it that way his life sounds pretty damn shitty.

@MeshGearFox  
Uh…I’m just gonna assume you got that backwards.

@Poptard  
Do not question shipping!

@Poptard  
It’s like with Rincewind in the Discworld novels. His mother ran away from home before he was born.

@MeshGearFox  
She… impregnated a male?

@Mayojar77
 
I think that Suri is Diamond Tiara’s mom. like maybe she got Filthy Rich pregnant in a one night stand or something.

@FanOfMostEverything  
That, and we don’t know if Rainbow ever knew her mother. Diamond Tiara’s only known relative is her father, we haven’t seen hide nor hair of anyone related to Silver Spoon, Twist, Pipsqueak, Snips or Snails.

Scootaloo and Fluttershy are both in a state of parental uncertainty, Trixie’s family is anyone’s guess, we’ve never seen another member of Zecora’s entire species…
 
You’re not the only pony with family problems, AJ.

I feel this could be longer.

… Stiiiiill ship it.