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Cancer shouldn’t really be a problem in Equestria
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Well, SOMEBODY has to get to be the wizard.
Also, I think you’re not giving the others enough credit. There must be a reason all three basic ponies are even, and don’t forget they didn’t get along before. Also, do bear in mind that Pinkie is an Earth pony.
Maybe in a couple or three decades, glioblastomas like those may be /almost/ as easily cured as that.