@Beau Skunky
 
I figured the picture of George Carlin would be a clue.

@Spearmint  
I don’t think there’s any reason for any of them to be those things, but wasn’t Dashie quite fond of Zap-Apple jam? (This situation might’ve killed her love for that though.)
 
You are what you eat.

Do you know why Rainbow Dash is a zap apple?
 

Okay. Now I know they’re taking drugs whilst making the comics.

@DashingJack  

@redweasel  
Because she’s the only “mane” character left, (besides Spike, but he’s probably a Pitaya for all we know) and because Applejack is the most loyalest, and dependable of ponies.

@PonyPon
 
why the deuce is everyone asking applejack to save them, then?
 
bad cider makes way more sense than that

Oh, great. There doing a ripoff of Crying Breakfast Friends.
 
Presenting IDW’s Happy Produce Friends!

@Background Pony #BBC3  
About as much as it does when you’re a regular viewer.

@PonyPon
 
It really doesn’t make any sense, does it?

YOU CAN’T  

Is this VeggieTales now?!?!

Let the nicknaming commence!

Applejack needs to lay off the sauce!

And as always, Pinkie’s perfectly happy in the midst of a crisis…

@PonyPon  
Might be the evil fruit hat actually. >>856690

And that’s why you shouldn’t do drugs, kids!

Welp that one person who was trying to make “Twilight is an eggplant” a thing, was successful in his attempts after all. Also Dash reminds me of a zappapple now :p

The medication isn’t working.

@Mugen Kagemaru  
Nope, just a thing that happened in the last FF.
 
Not even a part of the main story.

@PonyPon
 
Ongoing arc?

@Mugen Kagemaru  
Sweetie is accidently turning everyone into fruits and vegetables.

@PonyPon
 
Welp, in that case, hit me. What the hell’s going on here?