The human body isn’t designed to sit at a computer or look at a screen. These things can only be made tolorable.
We are hunter gatherers, and have evolved to spend a decent part of the day walking, our skeletal muscles play a big role in circulation and how tissues respirate. Periods of exercise and higher heart rate promote the production of cellular signals which can make more neurotransmitters available.
Screen light at night can confuse the pineal gland. This gland uses light from the optic nerve to decide whether or not to make melatonin, light tells it to stop, which increases adrenaline.