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Leonardo left fewer than 30 paintings, and most of them were never finished.
He was an experimenter, a perfectionist, and a procrastinator. He repeatedly painted over paintings over and over - destroying his previous work as he experimented with new looks or new backgrounds or different lighting.
He "deleted" the Mona Lisa repeatedly over the 16 years he fiddled with it, trying to perfect it, reworking the background and adding layer after layer after layer of new art on top of it.
Not onldy WOULD he delete the Mona Lisa, he actually did - repeatedly - trying to perfect it.
Leonardo was almost never happy with his own work, and even after something he'd created was "complete" he'd redo it again and again.
If Leonardo was an artist today and had art on this website it is without question that he'd be one of the most prolific pro-takedown artists on the site. He would be one of those people who took down commissions he did for other people because he wanted to fix it some more or because it wasn't perfect, or because one person downvoted it.
Beyond that, if an artist wants their art taken down, it's their choice. They retain their rights.